The purpose of the present study was therefore to determine the correlation between cognitive screening scores and gait parameters in patients with cognitive impairment using objective gait measurements. However, to our knowledge no previous study has investigated the correlation between gait parameters and scores on cognitive screening tests such as the MMSE and MoCA in patients with cognitive impairment. This makes it possible to assess not only the cognitive function but also the gait status in the elderly, with appropriate interventions then being applied if necessary. 14īased on this evidence, the gait status is well reflected in cognitive screening tests that assess executive function. 11, 12, 13 Executive function is the cognitive domain that is most relevant to gait performance, and it plays a key role in the planning, goal-directed action, and coordination of complex locomotion. 10 The correlation between cognitive impairment and gait disturbance is well established, as reported in many recently published papers. 8 Gait deficits and falls are more common in patients with dementia than in cognitively normal elderly persons, 9 with the severity of gait disturbance being closely related to the severity of cognitive impairment. It is well known that gait impairment in the elderly is a major factor contributing to hospitalization, institutionalization, and death. Gait disturbance in the elderly, termed “senile gait,” has received considerable attention during the past decade. The MoCA is also known to be more sensitive than the MMSE for assessing MCI. 7 It has been demonstrated that the MoCA can sufficiently assess various cognitive domains such as executive function and attention that could not be assessed well using the MMSE. 6 To overcome this limitation, the Montreal Cognitive Assessment (MoCA) was developed in 2005 as a brief screening tool for MCI. 5 Furthermore, the MMSE is greatly influenced by education level and is not useful for illiterate patients. The ceiling effect is a limitation of measurement which cannot distinguish patients with from normal elderly. 4 However, the sensitivity of the MMSE for detecting MCI or early-stage dementia is insufficient due to a ceiling effect. The MMSE is both easy to apply and rapid. The Mini Mental Status Examination (MMSE), which was developed in 1975, is the most widely used screening tool in clinical practice. Therefore, a brief cognitive screening test that is easy to use in outpatient clinics is crucial for the early diagnosis of dementia. 3 This trend has resulted in recent research and health policy strategies focusing on the early diagnosis and identification of biomarkers of AD. 2 MCI is thus the prodromal state prior to AD. 1 Reportedly 1.0–2.5% of elderly people with normal cognition progress to dementia annually, while 10–15% of mild cognitive impairment (MCI) patients progress to AD within 5 years. Alzheimer's disease (AD) is the most common of the various etiologies of dementia. The incidence of dementia is increasing rapidly worldwide as populations age, which is increasing social burdens.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |